I'll get things started:
http://us.wii.com/soft_loz_tp.jspI can't believe Link fires his arrows right-handed! This is an outrage upon humanity! Who the heck was programming this thing?!
Edit: Ah hah! It must be configurable for handedness, like many of the new Wii games. He's swordfighting right-handed, too. The test players on that video page are apparently all dextral scum.
My righteous wrath is assuaged.
Edit 2: Nope, he's right-handed through the whole thing, without a choice. They mirrored every detail in the entire game late in the development cycle in order to cater to the majority audience, after noticing at the last E3 that right-handed players were having difficulty using their right hands to control Links left hand.
I am going to go somewhere and cry.
Edit 3: Wait! Apparently there may indeed be a mirror mode! Dammit! This suspense is killing me. Can I get confirmation from somebody who has the game already?